A Case of Community-Onset Bacterial Meningitis due to Extended-Spectrum Beta-Lactamase Producing Escherichia coli

Yusuke Yoshino, Kazunori Seo, Ichiro Koga, Takatoshi Kitazawa, Yasuo Ota


This is a case of community-onset bacterial meningitis caused by an extended-spectrum beta-lactamase-producing Escherichia coli that was resistant to ceftazidime, cefpirome, and aztreonam. Multidrug-resistant gram-negative bacilli, such as the E. coli in our study, are now spreading in many medical fields and may possibly become pathogens of community-onset meningitis. Our findings with this case and previously published reports indicate that empiric therapy with carbapenems may represent a suitable management option for future cases of meningitis due to gram-negative bacilli.

doi: http://dx.doi.org/10.4021/jmc1362e


Extended-spectrum beta-lactamase (ESBL); Meningitis; Carbapenem

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