Concomitant Use of Cyclobenzaprine and Psychotropic Medications

Nevio Cimolai

Abstract


    Cyclobenzaprine has been cited as a co-factor or cause in serotonin syndrome following co-ingestion of other psychotropic medications. An observational study was conducted for a cumulative consumption of this agent among patients for 24 years, 8 months; no evidence of serotonin syndrome or malignant neuroleptic disorder was apparent despite a variety of concomitant psychotropic medications used.



 doi:10.4021/jmc241w

Keywords


Cyclobenzaprine; Serotonin; Serotonin syndrome; Tricyclic; Toxicity

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