Renal Liposarcoma in a Patient Undergoing Radiotherapy in Childhood: A Case Report

Pedro Nazareth Aguiar Jr, Barbara de Souza Gutierres, Daiane Pereira Guimaraes


Soft tissue sarcomas are rare neoplasms, which account for less than 1% of adult malignancies. In addition, they account for only 2% of renal cancers. The main mesenchymal lesions of the kidney are benign and difficult to differentiate with well-differentiated sarcomas. The aim of this report was to present the experience of the Hospital Sao Paulo (HU/UNIFESP) in a case of well-differentiated liposarcoma, which affected the kidney of a young adult who has been treated with radiotherapy in childhood, as well as to raise the relevant literature. A 26-year-old male patient with a history of prostate rhabdomyosarcoma that has been submitted to surgical resection and adjuvant radiotherapy 23 years ago in the childhood was presented. He was asymptomatic during 22 years, then he developed back pain, and underwent investigation and one tumor was detected in the right kidney. Radical nephrectomy was performed with complete resection of the lesion and he is currently without evidence of disease recurrence. Renal liposarcoma usually has good prognosis and the treatment is based almost exclusively on tumor resection. The differentiation between primary renal or retroperitoneal site is important for the prognostic assessment of the disease. There is a relationship between exposure to radiation in childhood and the development of second malignancy in adulthood, especially soft tissue sarcomas. Metastases are rare in well-differentiated forms of the disease. Recurrences can be observed in 30% of all cases and have been described after 13 years of initial diagnosis, which justifies the extended follow-up of these patients.

J Med Cases. 2014;5(10):538-540


Sarcoma; Liposarcoma; Kidney; Neoplasm; Case report

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:   editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.