Primary Cerebral Lymphoma Causing Remitting and Relapsing Neurological Symptoms

Thomas Stoker, Adam Young, Tarik Massoud, Rikie Patani, Mark Manford


Primary CNS lymphoma is a rare variant of non-Hodgkins lymphoma. Incidence has increased over the past 3 decades, but the optimum treatment protocol is yet to be established. We report a 44-year old man who presented with left-sided numbness. Magnetic resonance imaging of the brain revealed a right hemisphere ill-defined mass. Within four months the patient experienced a spontaneous near-full recovery. From this time the patient deteriorated with increasing left hemiparesis. After several months, the patient developed lethargy and dyspnoea, with episodes of epistaxis and per rectal bleeding. Full blood count revealed a pancytopaenia. Trephine biopsy demonstrated evidence of marrow involvement by diffuse large B-cell lymphoma. The patient was diagnosed with primary CNS lymphoma with systemic involvement. We conclude that the spontaneous remission of symptoms should not discourage a diagnosis of PCNSL if consistent with clinical and radiological findings.

J Med Cases. 2013;4(6):420-423


Primary Cerebral Lymphoma Causing Remitting and Relapsing Neurological Symptoms

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:   editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.