Ipilimumab Associated Autoimmune Alveolitis Responding to Corticosteroids

Ankit R. Rao, Simon A. Grumett

Abstract


       Malignant melanoma is increasing in incidence and metastatic melanoma is extremely challenging to treat, although new targeted and immunotherapeutic options for treatment are emerging. One of these is the anti CTLA4 antibody ipilimumab which releases the ‘break’ on endogenous anti-melanoma T-cell responses leading to improved survival. It is associated with autoimmune toxicity, typically in the liver, skin and colon. We report here the case of an ipilimumab treated patient who developed autoimmune alveolitis due to the drug, which is only very rarely reported in association with this form of immune-modulating therapy.



doi: http://dx.doi.org/10.4021/jmc886w


Keywords


Ipilimumab; Melanoma; Alveolitis

Full Text: HTML PDF
 

Browse  Journals  

     

Journal of clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics

World Journal of Oncology

Gastroenterology Research

Journal of Hematology

Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity

Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research

Journal of Neurology Research

International Journal of Clinical Pediatrics

 

 

 

 

 

Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.            
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.journalmc.org   editorial contact: editor@journalmc.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.