Blastic Plasmacytoid Dendritic Cell Neoplasm With Leukemic Progression

Choladda V. Curry, Sergej N. Konoplev, Carlos Torres-Cabala, Amin Alousi, Madeleine Duvic, Jonathan L. Curry


Blastic plasmacytoid dendritic cell neoplasm (BPDN), previously described as blastic NK cell lymphoma and CD4+/CD56+ hematodermic neoplasm is an aggressive hematologic malignancy with poor prognosis. We report a patient with BPDN who developed multiple recurrences and eventually leukemic progression. The patient died of disease 31 months after initial diagnosis. Long term survival for BPDN is poor despite multiple regimens of chemotherapy and bone marrow stem cell transplant.




J Med Cases. 2012;3(6):337-339


Blastic Plasmacytoid dendritic cell neoplasm; Blastic NK cell lymphoma; CD4+/CD56+ hematodermic neoplasm; Leukemia; Stem cell transplant

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