Malignant Transformation in a Typical Epidermal Cutaneous Cyst

Koutsopoulos V. Anastasios, Giatromanolaki Alexandra, Karpouzis Anthony, Sivridis Efthimios


Although cutaneous epidermal cysts are very common, malignant transformation is a rare event. Even more rare is a change into squamous cell carcinoma. Such a case is presented in this report. The clinical and histological characteristics together with the differential diagnosis and the pathogenesis of this unexpected development are discussed. We recommend that all lesions presumed to be epidermal cysts should be completely excised and submitted for histological examination.

J Med Cases. 2012;3(4):254-256


Cutaneous epidermal cyst; Malignant transformation; Squamous cell carcinoma; Acantholytic

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