Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization in Bests Vitelliform Macular Dystrophy

Figen Batioglu, Emin Ozmert, Elcin Suren, Sibel Demirel


To evaluate the results of intravitreal ranibizumab injection in a case with choroidal neovascularization (CNV) in Bests vitelliform macular dystrophy with different imaging modalities. A 20-year-old male with the complaint of reduced vision in the right eye underwent complete ophthalmological examination including fluorescein angiography (FA), fundus autofluorescence (FAF) imaging. Macular scans were obtained with spectral optical coherence tomography (OCT). Best corrected visual acuity was counting fingers at 2 meters in the right eye. Fluorescein angiography and OCT confirmed the diagnosis of CNV associated with Bests vitelliform macular dystrophy. After 3 monthly injections of intravitreal ranibizumab, CNV regressed and macular edema disappeared. Visual acuity improved to 10/10. His condition remained stable for 3 years after treatment. We concluded that the intravitreal ranibizumab may be a new approach for the therapy of CNV in Bests vitelliform macular dystrophy. However, a long-term follow-up is warranted. Different imaging modalities help us to understand the different aspects of macular involvement in this disease complicated with CNV.

J Med Cases. 2012;3(4):250-253


estís vitelliform macular dystrophy; Fundus autofluorescence; Intravitreal ranibizumab; Optical coherence tomography

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:   editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.