Amphetamine Use Revealing Hypertrophic Cardiomyopathy in a Young Patient

Vulnet Misimi, Muhemin Mohammed, Konstantinos Stamou, Andreas Mitsis, Panagiotis Sakellaropoulos, Despoina Tounissidou, Stefanos G. Sakellaropoulos


Adrenergic overstimulation in long term can lead to a hyperdynamic myocardium and give rise to hypertrophy and ultimately to heart failure. Amphetamine use is a common cause of neurohormonal activation, which gives rise to such adverse cardiovascular events. However, hypertrophy of myocardium in young patients, even due to apparently obvious causes, should always be considered as a red flag and a further diagnostic downstream should take place, in order to exclude genetic causes. We present a case of a young man with chronic use of amphetamine and an incidental finding of hypertrophic cardiomyopathy.

J Med Cases. 2022;13(4):192-195


Myopericarditis; Hypertrophic cardiomyopathy; Sudden cardiac death; Cardiac MRI

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