Use of N-Acetylcysteine in Amphetamine-Induced Acute Liver Failure

Saif Affas, Mohamad Fekredeen Ayas, Ihab A. Kassab

Abstract


Acute liver failure (ALF) is a serious complication of many drugs. Amongst recreational drugs, cocaine, amphetamines and ecstasy (methylenedioxymethamphetamine) have been known to cause ALF as a complication. However, the true effects and management on the liver of such cases have not been well reported and treatment of such conditions needs prompt action. N-acetylcysteine (NAC) is a known hepatoprotective agent but remains controversial in the use of recreational drug-induced acute liver injury. We present a case of ALF secondary to amphetamine ingestion, with a rapid recovery after administration of intravenous NAC.




J Med Cases. 2021;12(2):54-56
doi: https://doi.org/10.14740/jmc3611

Keywords


Acute liver failure; NAC; Amphetamine

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