Functional Mediastinal Paraganglioma Irrigated by Coronary Artery Collaterals Associated With Bilateral Renal Artery Fibro-Dysplasia in a Hypertensive Patient

Khaled Elenizi, Rasha Alharthi, Anthony Matta, Michel Galinier


We present a symptomatic functional anterior mediastinal paraganglioma (PGL) in a 56-year-old woman. The patient was known to have renovascular resistant hypertension caused by fibromuscular dysplasia diagnosed several years ago. The diagnosis of PGL was confirmed by 123I-metaiodobenzylguanidine scintigraphy, 18F-FDOPA positron emission tomography/computed tomography and a thoracic tomographic scan which revealed an anterior mediastinal tumor. Complete tumor resection was done through a sternotomy and extracorporeal circulation with cardiac arrest. The histological examination of the operative specimen was characteristic of PGL.

J Med Cases. 2019;10(10):296-301


Mediastinal paragangliomas; Renal artery stenosis; Fibromuscular dysplasia; Coronary vessel irrigation

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