Spontaneous Tumor Lysis Syndrome: A Rare Presentation in Breast Cancer

Muhammad Idrees, Saeeda Fatima, Eric Bravin

Abstract


Tumor lysis syndrome (TLS) is considered an oncologic emergency which requires early diagnosis and treatment to prevent mortality and morbidity. It refers to the constellation of metabolic disturbances manifested by acute renal failure associated with hyperuricemia, hyperkalemia, hypocalcemia and hyperphosphatemia. Diagnosis is made based on Cairo-Bishop clinical and laboratory criteria. Spontaneous TLS, occurring prior to the initiation of cancer therapy, has been reported in hematologic malignancies like high grade non-Hodgkin’s lymphoma (NHL) and acute leukemia, and rarely in solid tumors including colon cancer, hepatocellular carcinoma and in at least two cases of breast cancer. We present a case of spontaneous TLS in breast cancer patient which is rare but interesting disease manifestation.




J Med Cases. 2019;10(1):24-26
doi: https://doi.org/10.14740/jmc3237

Keywords


Tumor; Breast; Adenocarcinoma; Tumor lysis; Syndrome; Spontaneous; Oncologic emergencies; TLS

Full Text: HTML PDF
 

Browse  Journals  

     

Journal of clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics

World Journal of Oncology

Gastroenterology Research

Journal of Hematology

Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity

Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research

Journal of Neurology Research

International Journal of Clinical Pediatrics

 

 

 

 

 

Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.            
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.journalmc.org   editorial contact: editor@journalmc.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.