Leukostasis-Related Fatal Cardiopulmonary Arrest as Initial Chronic Myeloid Leukemia Presentation

Konstantinos Katogiannis, Ignatios Ikonomidis, Fotios Panou, Andreas Katsimardos, Aspasia Divane, Argyrios Tsantes, Efstathios Iliodromitis, Elias Kyriakou

Abstract


Chronic myeloid leukemia (CML) is a BCR-ABL1-positive myeloproliferative neoplasm (MPN), which is usually diagnosed in chronic phase (CP-CML) and is considered curable in the era of tyrosine kinase inhibitors (TKIs). Leukostasis is an urgent complication more often of acute and less often of chronic leukemias. Regarding CML, leukostatic symptoms are uncommon in CP and in newly diagnosed patients, while being more often in advanced disease stages (accelerated or blastic phase). Leukostasis in CML is mostly presented with neurologic or respiratory symptoms. We present here a case of newly diagnosed CML in CP, which initially presented with leukostasis-related fatal cardiopulmonary arrest in a 59-year-old woman.




J Med Cases. 2018;9(3):77-82
doi: https://doi.org/10.14740/jmc2993w


Keywords


Chronic phase CML; Leukostasis; Cardiopulmonary arrest

Full Text: HTML PDF
 

Browse  Journals  

     

Journal of clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics

World Journal of Oncology

Gastroenterology Research

Journal of Hematology

Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity

Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research

Journal of Neurology Research

International Journal of Clinical Pediatrics

 

 

 

 

 

Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.            
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.journalmc.org   editorial contact: editor@journalmc.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.