Tumor Lysis Syndrome as a Consequence of Chronic Lymphocytic Leukemia Treatment With Fludarabine and Rituximab

Firas Yazigi, Anuradha Kolluru, Ayad M Al-katib

Abstract


A seventy-nine year old Caucasian male with a diagnosis of chronic lymphocytic leukemia presented with acute tumor lysis syndrome after treatment with two courses of fludarabine and one course of rituxan. In this article we report this rare complication, which has been reported only few times in the literature, and discuss the ways to prevent it from happening.




J Med Cases. 2011;2(5):188-189
doi: https://doi.org/10.4021/jmc239w


Keywords


Tumor lysis syndrome; Chronic lymphocytic leukemia; Treatment; Fludarabine; Rituximab

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