A Case of Thyroid Hemiagenesis Associated With Graves’ Disease and Follicular Neoplasm

Bu Kyung Kim, Ju Won Lee, Min Jung Jung, Eun Mi Lee, So Young Ock, Su Kyoung Kwon, Young Sik Choi


Thyroid hemiagenesis is a rare congenital anomaly in which the thyroid lobe fails to develop, and the occurrence of thyroid hemiagenesis with other thyroid diseases is possible. Here, we report a case of thyroid hemiagenesis with Graves’ disease and follicular neoplasm. Our patient, an 81-year-old female, was admitted with general weakness and weight loss over the previous month. Laboratory testing showed elevated free T4, suppressed TSH, and elevated TSH receptor antibody levels. A 99mTc thyroid scan showed absent uptake in the left lobe and a cold nodule on the isthmus of the thyroid gland. Ultrasound imaging showed an oval-shaped thyroid nodule on the isthmus and diffuse enlargement and hypervascularity of the right lobe. We performed ultrasound-guided fine needle aspiration, and cytologic analysis showed evidence of a Hurthle cell follicular neoplasm. To date, this is the first reported case of thyroid hemiagenesis associated with Graves’ disease and Hurthle cell follicular neoplasm.

J Med Cases. 2015;6(8):385-387
doi: http://dx.doi.org/10.14740/jmc2189w


Hemiagenesis; Graves’ disease; Follicular neoplasm

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