Catastrophic Acute Thrombotic Occlusion During Fractional Flow Reserve Measurement

Arihide Okahara, Daigo Mine, Kenji Sadamatsu


This report describes a patient presenting with thrombotic occlusion of the left circumflex artery as a complication associated with the measurement of the fractional flow reserve. When we measured the fractional flow reserve with a pressure wire through a 5-Fr diagnostic catheter to assess myocardial ischemia in the left anterior descending artery, the pressure wave showed a damping curve. Then, the patient collapsed, and a coronary angiogram showed thrombotic occlusion of the proximal circumflex artery. The thrombus was successfully retrieved by means of ballooning and thrombectomy, and thereafter the coronary flow recovered.

J Med Cases. 2015;6(6):279-281


Complication; Coronary intervention; Intravascular ultrasound; Thrombus

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