Mucinous Tubular and Spindle Cell Carcinoma of the Kidney: Four New Cases

Abstract

Mucinous tubular and spindle cell carcinoma of the kidney is a rare and a recently described tumor with a favorable prognosis. Herein, we report four new cases. Four cases of mucinous tubular and spindle cell carcinoma of the kidney were diagnosed in our Department of Pathology (Farhat Hached hospital, Sousse, Tunisia). Histological slides and medical records were reviewed for morphologic and clinical data. The histological diagnosis was established according to the WHO classification system. The 2002 TNM system was used for pathologic staging. The median age of the four patients was 50 years, 2 patients presented with a unilateral flank pain and the tumor was asymptomatic in the 2 other cases. Tumors were well circumscribed on imaging exploration. All patients were treated by nephrectomy (radical in 2 cases and partial in 2 cases). Grossly, tumors presented as well-circumscribed solid masses, contained in the renal capsule in all cases. The mean tumor size was 4.5 cm. The histological diagnosis of mucinous tubular and spindle cell carcinoma was performed in all cases according to the WHO classification system. The four cases were pT1N0M0. The mean follow-up was 31 months and during this period, none of the patients developed recurrence or metastases. Mucinous tubular and spindle cell carcinoma of the kidney is a rare and a distinctive renal tumor with a relatively indolent behavior.




J Med Cases. 2010;1(1):18-20
doi: https://doi.org/10.4021/jmc113e