Multiple Arthralgia After Use of Amoxicillin in EBV Infection: Could it be Adult Onset of Still’s Disease?

Rachel WC Ng, Chi Eung Danforn Lim, Nga Chong Lisa Cheng


This case discusses about a rare development of adult-onset of still’s disease in a 39-year-old male patient after taking amoxicillin for 14 days in an upper respiratory infection setting. It was confirmed later that he was in fact suffering from EBV infection at that time. Adult Onset Still’s Disease (AOSD) is a rheumatic disease that tends to affect young adults between the ages of 16 and 35. This article presents an uncommon case of AOSD after use of amoxillcin with EBV infection. Still’s disease is thought to be triggered by external infectious agents in genetically predisposed hosts, with many clinical manifestations of AOSD similar to those of self-limited viral infections. Major clinical manifestations include transient fever, rash, arthralgia and arthiritis, myalgia and liver abnormalities. Diagnosis of AOSD is typically based on clinical observation. Treatment for AOSD is empirical and centers on the use of NSAIDs, steroids and disease modifying anti-rheumatic drugs.

J Med Cases. 2014;5(2):105-107


Athralgia; Antibiotics; Still’s disease

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics


World Journal of Oncology

Gastroenterology Research

Journal of Hematology


Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity


Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research


Journal of Neurology Research

International Journal of Clinical Pediatrics



Journal of Medical Cases, monthly, ISSN 1923-4155 (print), 1923-4163 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:   editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.