Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 3, Number 1, February 2012, pages 43-48

Silent Somatotroph Adenoma: A Morphologic, Immunohistochemical and Electron Microscopic Study: A Case Report


Figure 1.
Figure 1. Preoperative T1- weighed MRI with contrast enhancement (A: axial; B: coronal; C: sagittal.). Post operative T1-weighed MRI with contrast enhancement showing resection of the intrasellar portion of the tumor (D: axial; E: coronal; F: sagittal.). Octreoscan images shows lesion (G: axial; H: coronal; I: sagittal.). T1-weighted MRI with contrast enhancement scans 3 months after surgery and Octreotide treatment shows 20% shrinkage of tumor size. (J: axial; K: coronal; L: sagittal)
Figure 2.
Figure 2. No major cellular and nuclear pleomorphism was seen and mitotic figures were not obvious (Original magnification × 400).
Figure 3.
Figure 3. Immuno-positivity for GH in several unevenly distributed adenoma cells (original magnification × 400).
Figure 4.
Figure 4. Typical tumor cells having large nucleus, prominent dense nucleolus, but very little heterochromatin (× 7000).
Figure 5.
Figure 5. Electron micrograph depicting tumor cells containing collapsed inactive Golgi membrane, but no fibrous body was noted in Golgi area (×15000).