Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 14, Number 7, July 2023, pages 232-236


Extreme Hypernatremia due to Dehydration

Tables

Table 1. Basic Metabolic Profile on Admission, 24, 48, 72, and 96 h
 
Normal rangeOn admission24 h48 h72 h96 h
BUN: blood urea nitrogen.
Sodium (mmol/L)136 - 145191182171164157
Potassium (mmol/L)3.5 - 5.15.13.93.53.13.3
Chloride (mmol/L)98 - 107> 150> 150146137128
CO2, venous, mmol/L22 - 301817152119
Anion gap (mmol/L)< 18< 23< 1710610
Glucose (mg/dL)70 - 9916223620415597
BUN (mg/dL)8 - 2611931314427
Creatinine (mg/dL)0.7 - 1.33.172.92.271.431.13
Albumin (g/dL)3.5 - 53.52.72.62.22.3

 

Table 2. Summary of Case Reports on Severe and Extreme Hypernatremia
 
Author/yearPatient’s age (years)EtiologyNa+ level
DM: diabetes mellitus; HD: hemodialysis.
Ofran et al, 2004 [8]20Exorcism (use of salt solution)255 mmol/L
Metheny et al, 2020 [9]34Salt solution was used as anti-emetic196 mmol/L
Turk et al, 2005 [10]69Salt solution given as anti-emetic175 mmol/L
Furukawa et al, 2011 [11]55Intentional ingestion of depressed patient by drinking 700 mL of Japanese soy sauce (shoyu)187 mmol/L
Yamazaki et al, 2000 [12]60Intentional ingestion of psychotic patient by drinking 1 L bottle of shoyuEstimated at more than 177 mmol/L at the time of death
Carlberg et al, 2013 [13]19College prank, ingesting a quart of soy sauce182 mmol/L
Xiao et al, 2019 [14]58Undiagnosed DM191 mmol/L, corrected 202 mmol/L
Ju et al, 2013 [15]20Self-administered to lose weight and improve digestion174 mmol/L
Moder et al, 1990 [16]41Ingestion of supersaturated salt water solution intended for gargling209 mmol/L
Mohtadi et al, 2015 [17]33Emetic (self)175 mmol/L
Machino et al, 2006 [18]73Suicide188 mmol/L
Nur et al, 2014 [19]85Dehydration due to poor oral intake (dementia)187 mmol/L
Choi et al, 2013 [20]40Paranoid adipsia172 mmol/L
Bhosle et al, 2015 [21]54Iatrogenic from wrong bicarb concentration during HD207 mmol/L