Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc
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Case Report

Volume 3, Number 1, February 2012, pages 39-42

Secondary Hairy Cell Leukemia in a Patient With Chronic Myelogenous Leukemia Following Treatment With Tyrosine Kinase Inhibitors: Report of an Extremely Rare Case and Review of the Literature


Figure 1.
Figure 1. A) Hairy cells in the peripheral blood; B) Bone marrow biopsy showing involvement by atypical lymphoid cells; C) CD20; D) TRAP.
Figure 2.
Figure 2. A) FISH demonstrating absence of BCR-ABL1 fusion in the CD20-positive hairy cells; B) Presence of BCR-ABL1 fusion in CD20-negative granulocytes.