Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 11, Number 12, December 2020, pages 375-378

Multisystemic Inflammatory Syndrome in Children Associated With SARS-CoV-2 Infection: A Case Series Report in a Pediatric Center in Mexico


Table 1. Overview of the Various Series With Multisystemic Inflammatory Syndrome in Children
AuthorToubiana et al, 2020 [9]Whittaker et al, 2020 [10]Feldstein et al, 2020 [11]Davies et al, 2020 [12]Belhadjer et al, 2020 [13]
SARS-CoV-2: severe acute respiratory syndrome coronavirus 2; IVIG: intravenous immunoglobulin; KD: Kawasaki disease; KDSS: KD shock syndrome; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; AST: aspartate aminotransferase; ALT: alanine aminotransferase, LDH: lactate dehydrogenase; DD: D-dimer; NT-proBNP: N-terminal pro-brain-type natriuretic peptide; CAA: coronary artery abnormalities; NA: not available; IL: interleukin.
Median age (year)7.998.31110
Male (%)4366626651
KD complet/incomplete (%)55/NA22/NA20.4/19.3NA-
KDSS (%)57%--NA-
Epidemiological contact (%)4829.5NA37
SARS-CoV-2 positive (%)9078706488.5
Gastrointestinal system (%)10045-53929083
Shock (%)5750NA8780
Myocardial dysfunction (%)763133NA72
Neurological system (%)2926787NA
Laboratory findings↓ Lymphocytes, albumin and serum sodium; ↑ CRP, procalcitonin, ALT, DD, NT-proBNP and IL-6↓ Lymphocytes, albumin serum; ↑ CRP, ferritin, neutrophils, troponin I and NT-proBNP↓ Lymphocytes, albumin serum and platelets; ↑ CRP, neutrophils, ferritin, DD, fibrinogen, troponin I and NT-proBNP, and ALT↓ Lymphocytes, platelets; ↑ CRP, ferritin, DD and troponin I↓ Lymphocytes; ↑ CRP, troponin I, ferritin, DD and IL-6
CAA (%)24NANA3617
Coronary aneurisms (%)014.58230
IVIG (%)10071777671
Second dose IVIG (%)24NA21NA2.8
Systemic steroids (%)4864497334
Fluid resuscitation (%)5279NA92NA
Vasoactive and inotropic agents (%)7147488380
Mechanical ventilation (%)5243204662
Biologic therapy (%)01921228
Anticoagulation therapy (%)00475065
Death (%)0222.50