Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 11, Number 7, July 2020, pages 211-214


Macrophage Activation in COVID-19 Patients in Intensive Care Unit

Figure

Figure 1.
Figure 1. Bone marrow sample (magnification, × 50). May-Grunwald-Giemsa staining of bone marrow aspirate shows two histiocytes with engulfed nucleated cells (one neutrophil (green arrow) and one erythroblast (red arrow)).

Table

Table 1. Clinical and Laboratory Parameters
 
Patient 1Patient 2Patient 3Patient 4Patient 5Patient 6
F: Female; M: male; NR: normal range; ASAT: aspartate amino transferase; MAS: macrophage activation syndrome; CRP: C-reactive protein; PCT: procalcitonin.
GenderFMMFMM
Age676363516967
Maximum temperature (°C)36.138.14138.237.538.9
Hepatomegaly, splenomegaly, lymphadenopathyNoNoNoNoNoNo
Leukocytes (109/L) (NR: 4.49 - 12.68)13.023.710.377.49.12.5
Hemoglobin (g/dL) (NR: 11.9 - 14.6)11.18.513.58.310.07.8
Platelets (109/L) (NR: 173 - 390)3789532173971
Fibrinogen (g/L) (NR: 2.13 - 4.22)1.62.15.24.65.97.3
Ferritin (ng/mL) (NR: 36 - 220)6204,8991,0643568011,206
Triglycerides (mmol/L) (NR: 0.5 - 1.7)1.155.622.657.241.371.62
ASAT (UI/L) (NR < 37)4384107227124
H-score8420714714835102
Probability of MAS%0.5692.1022.023.00.101.70
Lymphocytes (109/L) (NR: 1.26 - 3.35)1.261.610.780.530.860.29
CRP (mg/L) (NR: 0 - 3)20827875223129213
PCT (ng/mL) (NR < 0.5)20105125.3108.20.93.1
DeathYesYesYesNoYesNo