J Med Cases

Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc

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Case Report

Volume 9, Number 9, September 2018, pages 281-283

Unusual Laboratory Results Suggest Late Development of Zika Virus-Specific Neutralizing Antibodies

Table

**Table 1.** List of Zika Laboratory Tests Performed on Patient A and Their Results. The First Specimen Was Drawn 8 days After Arrival From an Area of Zika Risk, and the Second Specimen Was Drawn 74 Days After Arrival in the USA
Specimen	Laboratory	Test performed	Result
Laboratories A, B, and C all refer to Public Health laboratories. NAT: nucleic acid testing referring to reverse transcriptase polymerase chain reaction (RT-PCR); IgM: immunoglobulin M referring to enzyme-linked immunosorbent assay (ELISA) testing the presence of IgM antibodies; PRNT: plaque reduction neutralization test.
First specimen	A	Zika NAT	Negative
First specimen	A	Zika IgM	Presumptive positive
First specimen	B	Zika NAT	Positive
First specimen	B	Zika IgM	Presumptive positive
First specimen	C	Zika PRNT	< 1:10 (negative)
First specimen	C	Dengue PRNT	< 1:10 (negative)
Second specimen	A	Zika NAT	Negative
Second specimen	A	Zika IgM	Presumptive positive
Second specimen	B	Zika NAT	Negative
Second specimen	B	Zika IgM	Presumptive positive
Second specimen	C	Zika PRNT	≥ 1:20 (positive)
Second specimen	C	Dengue PRNT	< 1:10 (negative)