Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc
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Case Report

Volume 8, Number 1, January 2017, pages 20-23


First Report of Treatment of Chronic Lymphocytic Leukemia in a Patient With Cystic Fibrosis

Table

Table 1. Treatment Protocol
 
CycleTherapyComplications
Treatment course 1: August 2013 - January 2014
1Bendamustine 100 mg/m2 (25% dose) × 2 days
IVIG 400 mg/kg prophylaxis
Acyclovir prophylaxis
Septra DS tab M/W/F prophylaxis
Renal dysfunction from acyclovir therefore discontinued
2Bendamustine (50% dose) × 2 days
IVIG 400 mg/kg
Septra DS tab M/W/F
3Bendamustine (70% dose) × 2 days
IVIG 400 mg/kg
Septra DS tab M/W/F
4Bendamustine (70% dose) × 2 days
IVIG 400 mg/kg
Septra DS tab M/W/F
5Bendamustine (100% dose) × 2 days
IVIG 400 mg/kg
Septra DS tab M/W/F prophylaxis
6Bendamustine (100% dose) × 2 days
IVIG 400 mg/kg
Septra DS tab M/W/F
Treatment course 2: February 2015 - present
-Ibrutinib 420 mg daily
IVIG 400 mg/kg monthly
March 2015: Ascending cholangitis, Enterococcus bacteremia requiring hospital admission and IV piperacillin-tazobactam. Biliary stricture NYD requiring stenting.
April 2015: respiratory symptoms responding to a 2-week course of doxycycline