Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 6, Number 12, December 2015, pages 554-558

Endometrioid Adenocarcinoma Arising From Adenomyosis in a Premenopausal Woman: A Case Report


Figure 1.
Figure 1. CT revealed multiple lung (a) and liver metastasis (b). MRI of the pelvis before admission. Sagittal (c) and frontal (d) T2-weighted image demonstrates multiple tumors in uterine myometrium and omentum.
Figure 2.
Figure 2. Macroscopic findings of the uterus (a, b), omentum (c), and liver (autopsy) (d). The uterus was child-head sized with multiple nodular lesions and the endometrium appeared normal (a, b). Multiple disseminations in omentum (c) and liver (d) were seen.
Figure 3.
Figure 3. Histopathological analysis of the uterine specimen. Poorly differentiated endometrioid adenocarcinoma with squamous differentiation was within uterine myometrium (hematoxylin-eosin (H&E), original magnification × 20) (a). Cancer nests adjacent to the adenomyotic foci were observed (H&E, × 20) (b). Adenomyosis was seen in myometrium (H&E, × 10) (c). The endometrium was unremarkable (H&E, × 20) (d). Immunohistochemical examination: tumor cells stained positively for p53 (g), but did not express either ER (e) or PR (f).