Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 7, Number 3, March 2016, pages 81-83

Lactate Dehydrogenase and Ferritin Levels: A Clinical Clue for Early Diagnosis of Disseminated Histoplasmosis in HIV Patients


Figure 1.
Figure 1. Microscopic slide of histoplasmosis: sputum samples were positive for candida (normal colonizer) and histoplasmosis.
Figure 2.
Figure 2. Chest X-ray for pre-treatment and post-treatment.


Table 1. Literature Review Showing Relation of LDH With Disseminated Histoplasmosis
No. and dates of casesElevated LDH
104 cases reported in Panama city with disseminated LDH, 200677 patients out of 104 were found to have elevated LDH three times the upper normal limit
15 cases reported in Texas, 1996All patients had elevated LDH
4,376 cases in a retrospective study in New York, 1993 - 1997LDH was elevated in 80% of patients
24-year-old male with disseminated histoplasmosis, a case report, 2006LDH elevated
HIV with disseminated histoplasmosis, a case report, 1997LDH elevated
72 cases were reported in Europe, 2006LDH was elevated but the no. or percentage of patients with elevation was not specified