J Med Cases

Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc

Journal website http://www.journalmc.org

Case Report

Volume 2, Number 3, June 2011, pages 127-131

The Surgical Treatment for Recurrent Liposarcoma of the Hypopharynx in a Pregnant Woman

Figure 1. The endoscopy of the hypopharynx revealed a smooth tumor involving the pyriform sinus and aryepiglottic folds.

Figure 2. MRI showed a moderately heterogeneous mass spreading submucosally around the right pharynx and pyriform sinus. (A) T1 weighted image, (B) T2 weighted image, (C) fat suppression of the T1 weighted image. The white arrows show the tumor mass.

Figure 3. Pathological study. (A) Neoplastic lobules traversed by fibrous bands and composed of adipocytes of varying size (H&E, x 40). (B) Fat cell and spindle cells with enlarged and atypical nuclei were observed in the lobules (H&E, x 200).

**Table 1.** Clinicopathological Data for Cases With Hypopharyngeal Liposarcoma
Author	Age	Sex	Location	Histology	Size (cm)	Initial treatments	Outcome/follow up period	Additional treatments
PS: pyriform sinus; Well: well-differentiated liposarcoma; Myxoid: myxoid type liposarcoma; Size: maximum length; RT: radiotherapy; CRT: chemo- and radiotherapy; Rec/: recurrence/time to recurrence; No rec/: no recurrence/follow up period; -: not written precisely in the literature.
Kapure [2]	61	M	PS	Myxoid	-	-	Died/1 y	-
Thomas et al [3]	62	M	PS	Well	6.5	Endoscopic excision	No rec/1 y
Wenig et al [4]	60	M	PS	Well	2	Endoscopic excision	Rec/5 y	Total laryngectomy
Wenig et al [4]	59	M	PS	Well	5.5	Endoscopic excision	Rec/6 m	Lateral pharyngotomy
Wenig et al [4]	46	M	PS	Well	-	Lateral pharyngotomy + RT	Rec/1 y	Total laryngectomy + RT
Wenig et al [4]	77	M	PS	Well	4	Endoscopic excision	Rec/3 y	Total laryngectomy
Wenig et al [5]	57	M	PS	Well	14	Endoscopic excision	Rec/-	Lateral pharyngotomy
Wenig et al [5]	25	M	PS	Well	-	Lateral pharyngotomy	No rec/1 y
Reed et al [6]	57	M	PS	Well	21.5	Lateral pharyngotomy	-
Wambeek et al [7]	60	M	PS	Well	3	Lateral pharyngotomy + CRT	No rec/1 y
Fahmy et al [8]	51	M	PS	Well	-	Lateral pharyngotomy	No rec/2 m
Mandel et al [9]	90	F	PS	Well	6.5	Endoscopic excision	No rec/9 m
Mouret [10]	56	M	PS	Well	10	Lateral pharyngotomy	Rec/2 m	Endoscopic excision
Luna-Ortiz et al [11]	23	M	PS	Myxoid	9.5	Lateral pharyngotomy	Rec/1 y	Endoscopic excision
present	38	F	PS	Well	3	Endoscopic excision	Rec/1 y	Lateral pharyngotomy, Endoscopic excision

Table 1. Clinicopathological Data for Cases With Hypopharyngeal Liposarcoma

Author

Age

Sex

Location

Histology

Size (cm)

Initial treatments

Outcome/follow up period

Additional treatments

PS: pyriform sinus; Well: well-differentiated liposarcoma; Myxoid: myxoid type liposarcoma; Size: maximum length; RT: radiotherapy; CRT: chemo- and radiotherapy; Rec/: recurrence/time to recurrence; No rec/: no recurrence/follow up period; -: not written precisely in the literature.

Kapure [2]

Myxoid

Died/1 y

Thomas et al [3]

Well

6.5

Endoscopic excision

No rec/1 y

Wenig et al [4]

Well

Endoscopic excision

Rec/5 y

Total laryngectomy

Wenig et al [4]

Well

5.5

Endoscopic excision

Rec/6 m

Lateral pharyngotomy

Wenig et al [4]

Well

Lateral pharyngotomy + RT

Rec/1 y

Total laryngectomy + RT

Wenig et al [4]

Well

Endoscopic excision

Rec/3 y

Total laryngectomy

Wenig et al [5]

Well

Endoscopic excision

Rec/-

Lateral pharyngotomy

Wenig et al [5]

Well

Lateral pharyngotomy

No rec/1 y

Reed et al [6]

Well

21.5

Lateral pharyngotomy

Wambeek et al [7]

Well

Lateral pharyngotomy + CRT

No rec/1 y

Fahmy et al [8]

Well

Lateral pharyngotomy

No rec/2 m

Mandel et al [9]

Well

6.5

Endoscopic excision

No rec/9 m

Mouret [10]

Well

Lateral pharyngotomy

Rec/2 m

Endoscopic excision

Luna-Ortiz et al [11]

Myxoid

9.5

Lateral pharyngotomy

Rec/1 y

Endoscopic excision

present

Well

Endoscopic excision

Rec/1 y

Lateral pharyngotomy, Endoscopic excision