Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc
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Case Report

Volume 6, Number 5, May 2015, pages 194-197

Prolonged Bradycardia Induced by Bevacizumab-Associated Infusion Reaction in Advanced Metastatic Colon Cancer


Figure 1.
Figure 1. Electrocardiography before the chemotherapy (1 month before the chemotherapy). Heart rate was 70/min, sinus rhythm.
Figure 2.
Figure 2. Electrocardiography on 1 day after the infusion reaction. Heart rate was 36/min, sinus rhythm.
Figure 3.
Figure 3. The course of the treatment of the second course FOLFOX4 plus bevacizumab.


Table 1. Laboratory Findings on the Previous Day of the Infusion Reaction
Hb10.2 g/dL
Plt26.9 × 104/μL
APTT29.4 s
D-dimer10.6 μg/mL
TP5.1 g/dL
UA2.4 mg/dL
BUN14.5 mg/dL
Cre0.66 mg/dL
TB0.5 mg/dL
γ-GTP66 U/L
CK76 U/L
ALP605 U/L
LDH488 U/L
Na137 mEq/L
Cl106 mEq/L
K4.5 mEq/L
Ca7.8 mEq/L
CRP4.34 mg/dL
CEA1,249 ng/mL (data upon admission)
CA19-95,310 U/mL (data upon admission)